Michael J. Mitchell News

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• Penn Engineers Redesign mRNA Delivery Vehicles to Boost Vaccine Potency and Slash Liver Toxicity

  Published: Mar 24, 2026

  Section: Science & Tech

  Researchers at the University of Pennsylvania have developed a new class of "aroLNPs" that utilize aromatic rings to steer mRNA vaccines directly to lymph nodes. This structural mo...

• Lipid Engineering Breakthrough Redefines mRNA Vaccines by Boosting Immune Metabolism and Eliminating Side Effects

  Published: Mar 17, 2026

  Section: Science & Tech

  University of Pennsylvania researchers have developed a new generation of lipid nanoparticles (LNPs) that go beyond simple delivery. By modifying the chemical structure of ionizabl...