University of Michigan Engineers Develop Protein Nanoparticles to Deliver Gene Therapy Without the Risks of Viral Vectors

University of Michigan researchers develop protein-based nanoparticles that genetically modify human cells without the side effects of viral vectors.

By: AXL Media

Published: Mar 31, 2026, 4:22 AM EDT

Source: Information for this report was sourced from University of Michigan

University of Michigan Engineers Develop Protein Nanoparticles to Deliver Gene Therapy Without the Risks of Viral Vectors - article image
University of Michigan Engineers Develop Protein Nanoparticles to Deliver Gene Therapy Without the Risks of Viral Vectors - article image

HEADLINE

University of Michigan Engineers Develop Protein Nanoparticles to Deliver Gene Therapy Without the Risks of Viral Vectors

SUMMARY

Researchers at the University of Michigan have successfully used protein-based nanoparticles to genetically modify human liver, kidney, and immune cells. This "artificial virus" alternative aims to treat cancers and genetic diseases without the dangerous side effects associated with modified viruses or lipid-based delivery systems, such as secondary cancers or systemic inflammation.

CONTENT

A Safer Vehicle for Genetic Medicine

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