Nutritional Study Links Vitamin E Intake to Lower Prolactin Levels in Women Seeking Fertility Care

New research shows Vitamin E intake is linked to lower prolactin levels in women seeking fertility care. Discover how B2 and calcium impact body composition.

By: AXL Media

Published: Apr 27, 2026, 6:50 AM EDT

Source: Information for this report was sourced from Scientific Reports and News-Medical.net.

Investigating the Role of Micronutrients in Conception

The relationship between everyday dietary choices and reproductive success is a growing area of clinical focus, particularly as one in six couples worldwide now faces infertility. A recent cross-sectional study conducted in Spain between 2022 and 2024 sought to determine if specific micronutrient intakes correlate with hormonal balance and body composition in women actively seeking fertility assistance. Unlike previous research focused on the general population, this study targeted 97 women aged 18 to 40 who met clinical criteria for infertility, excluding those with pre-existing conditions like endometriosis or polycystic ovary syndrome to isolate the effects of diet.

Vitamin E and Prolactin Regulation

One of the most significant findings of the research was the inverse association between Vitamin E intake and levels of prolactin. Prolactin is a hormone that, while essential for lactation, can interfere with normal ovulation and the menstrual cycle if levels are too high in women trying to conceive. Even after researchers adjusted for confounding factors such as smoking status, physical activity, and body mass index, the link between higher Vitamin E consumption and lower prolactin remained significant. This suggests that the antioxidant properties of Vitamin E may play a role in hormonal regulation, though researchers noted that a causal mechanism has not yet been definitively proven.

Micronutrients and Body Composition Markers

The study also highlighted how specific vitamins and minerals are linked to metabolic homeostasis and body fat distribution. Vitamin E intake showed an inverse correlation with hip circumference, hinting at a possible influence on regional fat distribution. Furthermore, riboflavin (Vitamin B2) and calcium were both positively associated with muscle mass percentage. Given that the average participant in the study fell within the overweight range with body fat percentages exceeding recommended levels, these findings suggest that optimizing B2 and calcium intake could support a more favorable body composition for reproductive health.