Global interdisciplinary team led by UC San Diego secures twenty-five million dollar grant to decode DNA mutational signatures

Team CAUSE, led by UC San Diego’s Ludmil Alexandrov, wins a $25M Cancer Grand Challenges award to map mutational signatures and the molecular origins of cancer.

By: AXL Media

Published: Mar 4, 2026, 9:29 AM EST

Source: The information in this article was sourced from University of California - San Diego

Source received: University of California - San Diego - Team led by UC San Diego researchers selected for prestigious global cancer prize. Ready to edit.

HEADLINE

Global interdisciplinary team led by UC San Diego secures twenty-five million dollar grant to decode DNA mutational signatures

SUMMARY

A multinational research group known as Team CAUSE has been awarded a Cancer Grand Challenges prize to investigate the molecular origins of cancer. Led by Professor Ludmil Alexandrov, the team will systematically map the chemical modifications to DNA that create unique mutational fingerprints, aiming to revolutionize cancer prevention and treatment strategies.

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